I Studied some important medical literatures inorder to examine the cause & syndrome of diffuse fluid-retention syndrome and found out some facts as follows ; 1. cause of diffuse fluid-retention syndrome is Hwang Je Nae Kyong(黃帝內經) and so forth six kinds of medicine books are reffered sudden thirst of intestin and stomark cause of disease Golden chamber(金?要略) and so forth fifteen kinds of medicine books are reffered fluid water promote obscesses atributide at four extrenities and unable hidrosis cause of disease Elementary cause for medicine(醫學入門) and so forth kinds of book medicine books are reffered water in four extrenities cause of disease. The classified Medical Records of Famous physicians(名醫類安) reffered rest at wetness earthly cause of disease. 2. syndrome of diffuse fluid-retention syndrome is Golden chamber and so forth nineteen kinds of medicine books are reffered compression and pain of body syndrome of disease. Hwang Je Nae Kyong(黃帝內經) and so forth seven kinds of medicine books are reffered pulse ; the liver-pulse is soft and powder syndrome of disease. The classified Medical Records of Famous physicians(名醫類安) and so forth two kinds at medicine book are reffered general syndrome of disease. Today is reffered edema of four extremites syndrome of disease. The cause & syndrome of diffuse fluid-retention syndrome obtained was as follows ; cause of diffuse fluid-retention syndrome is fluid water promote abscess attributide at four extremities and unable hidrosis and compression and pain body is main syndrome and hyperhidrosis, vertigo, edema of four extremities alternating episodes of chills and fever can guan pulse is sunken and slippery and both chi wiry are represented syndrome of diffuse fluid-retention syndrome.