To study on the water quality of domestic purifier, twenty four samples of clean water by purifier and the raw water(tap water) were tested for biological and physico-chemical examination and were checked for style of purification and the period elapsed after changing of purification medium. The results were as follows; Biological and physico-chemical findings of raw water were not exceeded standard values. Average number of general bacteria,2.coli and pH in clean water were significantly higher than that of raw water(respectively, p<0.01), but mean contents of turbidity, chloride, nitrate and iron in clean water were significantly lower than that of raw water(respectively, p<0.01). In general count of bacteria and E.coli, a half of the clean water of ceramic filter and roverse osmosis style were exceeded standard values for drinking water. All of the pH of the ion exchange style clean water were exceeded standard values. But other findings were within standard values. In average bacterial counts and physico-chemical findings of clean water by purification style of purifier, clean water of ion exchange style purifier were lowest number of general bacteria and not detected in 2. coli. But other items were highest. The longer period elapsed after changing of purification medium were the higher contents of biological and physico-chemical findings of clean water.