The term of stress was used by many scientists, but there were several difinitions about stress, and this term are using in societies frequently. Generally stress is defined as equilibrium, harmony, and adaptation to external stimulations, in 1930 s Hans Selye was the first scientist who used the term of stress and he pointed out the stress mean the function of force in body. When we get stress the stimulation go to the sympathetic-adrenomedulla system and epinephrine and norepinnephrine are secreted from adrenal medulla. Author tried to investigate the change of catecholamine secretion from rat urine which were exposed to 80 dB noise environment. The control rat urine released 0.03 $pm$ 0.01 ng/ml of epinephrine and 0.18 $pm$ 0.04 ng/ml, but in noise exposed group the epinephrine was 0.42 $pm$ 0.07 ng/ml and norepinephrine was 2.16 $pm$ 0.48 ng/ml.