We performed the effect of Oh-ja-yeun-jong-tang kami in patients with sperm deficience, reported as follows ; 1. The cause of sterility was sperm deficience of the man, The cause of Oriental medicine were classified into Sin Hyu(腎虧), Junghu(精虛), Kihyulyanghu (氣血兩虛) generally belong to Hujeong(虛證) in Oriental med. 2. The treatment ; Boshin(補腎), Bojung(補精), Boikgihyul(補益氣血). 3. The treatment effect of Oh-ja-yeun-jong-tang kami ; Bosinjunjung(補腎塡精), Egumsaengjin(益陰生津), Bogihyul(補氣血), Hwalhyulguea(活血祛瘀).