Extracorporeal shock wave lithotripsy(ESWL) offers a noninvasive alternative to surgery in the treatment of gallstones. However, there are still controversies about inclusion criteria for the selection of the patient, especially concerning the gallstone size, number and presence of calcification. We prospectively studied 63 patients with gallstones who underwent ESWL of the gallbladder using the EDAP LT. 01 lithotriptor during 10 months. Firty-two of 63 patients showed successful fragmentation of stones but six of the 11 failed patients did not show modification of size after the 5th session. According to diameter below 10mm, 10-20mm and over 20mm, the respective successful fragmentation rates were 100, 88.2 and 81.8%. According to number upto three and over three the respective successful fragmentation rates were 91.1 and 84.6% Finally according to the characterisitc of stone, the successful fragmentation rates were 88.0 for calcified stone group, while 90.9% for radiolucent stone group. Although the number of shock waves increased as the size and number of stones increased, however in cases of calcified stones, size, number and presence of calcification of gallstones did not affect the success rate of ESWL.