In this paper, the inter- and intra-frame distortions in the gray levels of a series of fluorescein ocular fundus photographs are corrected. For doing this, the background images are extracted from original images using the image blurring effect by decimation, and then shading corrected images are obtained by subtracting the background images from the original images pixel by pixel. In a series of fluorescein ocular fundus photographs, after the gray scale distoriton is corrected, the intensity volumes of dye leakage are measured and represented by a graph. These data may be useful for the prediction of prognosis and the therapeutic management.