The five patients with leiomyoma of esophagus were treated from 1976, to 1990. The patients were 4 men and 1 woman whose ages ranged from 28 to 53 years. One of them was asymptomatic, two had mainly dysphagia and the others complained indigestion and epigastric discomfort. There was no relationship between the severity of symptoms and the size of tumor. The preoperative diagnosis was made by esophagoscopy and esophagogram, and all of them were treated by thoracotomy and enucleation. There was no postoperative complication and the results were excellent.