Celiac Plexus neurolysis (C. P. N) has been commonly used to treat malignant pain of the abdominal area that is intractable. It relieves the pain effectively instead of using massive systemic narcotic analgesics. C. P. N. with modified transaortic technique was performed under C-T guidance, in which a single needle was advanced from a left posterior paramedian approach through the aorta in order to inject anesthetic agents directly into the celiac plexus. There was marked pain relief without any hemorrhagic and neurological or other complications. We found this modified transaortic method of C. P. N. to be very effective, safe and easy to perform compared with the classic two needle technique.