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대기중 Benzo(a) pyrene의 외삽방법에 따른 위해도 추계치의 비교 연구
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  • 대기중 Benzo(a) pyrene의 외삽방법에 따른 위해도 추계치의 비교 연구
  • A Study for Comparison of Risk Estimates According to Extrapolating Methods of Benzo(a)Pyrene in the Ambient Air
저자명
김종만,정용
간행물명
大氣保全 : 韓國大氣保全學會誌
권/호정보
1992년|8권 1호|pp.29-37 (9 pages)
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한국대기환경학회
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이 논문은 한국과학기술정보연구원과 논문 연계를 통해 무료로 제공되는 원문입니다.
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기타언어초록

The risk of benzo(a)pyrene for cancer in the ambient air of Seoul was assessed by using the extrapolation methods. The average daily lifetime exposure of benzo(a)pyrene in the ambient air of Seoul was calculated at 6.97-24.30ng/$m^2$/day, which was based on the occurrence analysis of benzo(a)pyrene in the residential(Bull Kwang Dong) and traffic areas(Shin Chon) of Seoul. Using the dose scaling based on body surface area in comparisons of toxicity for extrapolation from animal to human and mathematical models from the high dose region, the low-dose risk was estimated. The response probabilities were estimated by the tolerance distribution models; Probit, Logit and Weibull model. They were consistent with the observed ones at experimental dose region. The unit risk estimates of these models were too low to be used. One-hit and multistage model to prove more conservative risk was selected. As a redult, the lifetime unit risk of benzo(a)pyrene for cancer and virtually safe dose were calculated; One-hit model provided the risk 2.8 $ imes 10^{-7}$ and 3.4ng/$m^3$, respectively and multistage model provided 5.2 $ imes 10^{-7}$ and 1.9ng/$m^3$ as the more conservatives. The lifetime excess risk estimates of benzo(a)pyrene for cancer were calculated at 0.37-1.30 persons/million persons by one-hit model and 0.69-2.41 persons/million persons by multistage model, which was considered in without virtual risk.