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수술불능 및 재발성 직장암에 대한 중성자선 치료
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  • 수술불능 및 재발성 직장암에 대한 중성자선 치료
  • Neutron Therapy of Unresectable and Recurrent Rectal Cancer
저자명
류성렬,고경환,조철구,박우윤,윤형근,심재원,Yoo. Seong Yul,Koh. Kyoung Hwan,Cho. Chul Koo,Park. Woo Yun,Yun. Hyong Geun,Shim. Jae Won
간행물명
대한치료방사선과학회지
권/호정보
1993년|11권 1호|pp.127-132 (6 pages)
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대한방사선종양학회
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이 논문은 한국과학기술정보연구원과 논문 연계를 통해 무료로 제공되는 원문입니다.
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기타언어초록

Total of 53 patients of unresectable and recurrent rectal cancer treated with neutron beam during the period from Oct.1987 to Apr.1992 were analyzed. Dose fractionation for the neutron only group was 1.5 Gy per fraction,3 fraction per week,21 Gy/41/2 wks for 42 patients out of 53 ($76{\%}$). Neutron only but modified fractionation schedule ($10{\%}$ more or less of total dose) was applied for 9 patients, and mixed beam (neutron boost) was for 4 patients, Complete tumor response was obtained in 40 patients ($76{\%}$, response rate). Local control rate was 28 out of 53 ($53{\%}$). Statistically significant better prognostic factors for local control were age below 49 years old (15/22, $68{\%}$) than above 50 years old (13/31, $42{\%}$), male (20/32, $63{\%}$) than female (8/21, $38{\%}$), tumor size less than 5 cm and non-metastatic (16/24, $67{\%}$) than size more than 5 cm or metastatic (12/29, $41{\%}$). Major complication had developed in 7 patients ($13{\%}$). Two year overall survival rate by Kaplan-Meier method was $30{\%}$, but it was rised to, $47{\%}$ when the turner was less than 5 cm non-metastatic.