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  • 사지 악성 육종에서 보존적 수술후 방사선 치료의 역할
  • The Role of Conservative Surgery and Radiation Therapy for the Extremity Soft Tissue Sarcomas
저자명
김우철,서창옥,김귀언,박광화,신동환,이경희,Kim. Woo Cheol,Suh. Chang Ok,Kim. Gwi Eon,Park. Kwang Hwa,Shin. Dong-Hwan,Lee. Kyung Hee
간행물명
대한치료방사선과학회지
권/호정보
1993년|11권 2호|pp.411-419 (9 pages)
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대한방사선종양학회
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이 논문은 한국과학기술정보연구원과 논문 연계를 통해 무료로 제공되는 원문입니다.
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기타언어초록

A total of 44 patients with extremity soft tissue sarcomas had received conservative surgery and radiation therapy in the Department of Radiation Oncology, Yonsei Cancer Center, Yonsei University College of Medicine between Jan. 1980 and Dec. 1990. Initial surgical treatment consisted of intracapsular excision in 33 patients $(75\%),$ marginal excision in 9 patients, and wide excision in two patients. Total radiation doses were between 40Gy and 65Gy (median 60 Gy). Median follow-up period was 47 months. Overall actuarial 5-year survival rate was $76.9\%$ and 5-year recurrence free survival rate was $39.3\%.$ There was no statistically significant prognostic factors but the 5-year survival rates tended to be decreased in the patients with high grade tumors and treated with narrow surgical extent. Sixteen patients recurred during fellow-up (16/31, $51.6\%).$ The incidence of initial local recurrence was $22.6\%$ (7/31) and distant metastasis was $29\%(9/31).$ Of the 7 who did not have metastasis at diagnosis of local recurrence, 5 were submitted to a salvage treatment. All of them achieved local control and distant metastasis appeared in three of them. In conclusion, conservative surgery and radiation therapy in the patients with extremity soft tissue sarcomas was the effective treatment modality.