- 뇌폐흡충증의 영상진단에 관한 연구 : CT/MR 소견 및 ELISA 항체검사와의 상관성
- ㆍ 저자명
- 장기현
- ㆍ 간행물명
- 대한방사선의학회지
- ㆍ 권/호정보
- 1993년|29권 3호|pp.345-354 (10 pages)
- ㆍ 발행정보
- 대한영상의학회
- ㆍ 파일정보
- 정기간행물| PDF텍스트
- ㆍ 주제분야
- 기타
To evaluate the CT and MR findings of cerebral paragonimiasis (PW) and to assess the diagnostic value of the specific antibody test by enzyme-linked immunosorbent assay (ELISA) for PW, 55 CT scans and 13 MR images of 57 patients with cerebral PW were reviewed retrospectively, and correlated with the serum/CSF anstage (n=4), on the basis of CT/MR findings. In the group of early active stage the most common and characteristic finding was seen in 52% on CT and 44% on MR.Other non-specific findings included a solitary ring-like or irregular enhancing lesions, ill- defined low density lesions without enhancement, localized hemorrhage with or without enhancing lesions. In the group of chronic stage there were multiple calcifications of various shapes, most commonly 1-2cm sized round shape, and associated encephalomalacia. MR was superior to CT in detecting hemorrhage and in characterizing the central contents of ring-shaped calcifications, while it was inferior to CT in detecting hemmonly 1-2cm sized round shape, and associated encephalomalacia. MR was superior to CT in detecting hemorrhage and in characterizing the central contents of ring-shaped calcifications, while it was inferior to CT in identifying small calcifications. Antibody levels of serum and CSF were positive in 86% and 82% in early active group, and in 48% and 31% in chronic sgage, respectively. The positive rate was significantly different between the two groups (p=0.001). CT/MR findings were characteristic in only approximately half the cases in early active cerebral PW which can be cured by Praziquantel therapy. Therefore, antibody test by ELISA is recommended as a complementary tool, Particularly in patients with non-specific imaging findings.