Intussusception is the most common cause of acquired intestinal obstructions during infancy and early childhood. Barium reduction and pneumorduction have been used widely as nonsurgical method of treatment in radiologic department. In the past, attempts at barium reduction of intussusception were contraindicated in the presence of frank intestinal obsturction, shock, fever, dehydration, bowel perforation, peritonitis and longstanding symptoms. At present, however, there is no consensus regarding its application on patient on patient presenting with sign of frank intestinal obstruction. The authors analyzed the effect of pneumoreduction in the intussusception with sign of frank intestinal obstruction. Pneumoreduction was attempted in 53 cases of intussusception with sign of frank intestinal obstruction. Reduction was successful in 43 cases (81%) The mean fluroscopic time was 15.1 minutes and mean maximal pressure was 121.8mmHg in successful reduction, As complications, two cases of bowel perforation were observed, but could be treated surgically without any singificant problem. In conclusion, pneumoreduction is a useful substitute for barium reduction in the management of pediatric intussusception with sign of frank intestinal obstruction.