Active micro-vibration control of a structure, which simulates a stepper device, is performed using a pair of piezolectric actuators. The control aims at reducing the translational and rotational vibrations of the upper plate when the base is subject to seismic disturbance and the upper plate undergoes impulsive transient motion. Using the experimentally determined model, derivative control scheme is adopted so that the damping of the closed-loop system is effectively increased. It is found that the predicted control performance is in good agreement with the experimental results. Finally, the limit cycle phenomenon due to the controller voltage saturation is compared with the simulation.