This work has been investigated the ralationship between single surface crack length and crack depth have influence on the fatigue life. The simulation based on experimental results of 2.25 Cr-1Mo steel at various crack configuration ratios has enabled successful prediction of fatigue life at room temperature. The effect of crack depth should be considered for predicting fatigue crack growth rates as well as that of surface crack length. It is also shwn that the crack growth mechanisms are in good agreement with expreimental data according to the interaction of crack length and crack depth.