This paper deals with Hyang-Yak Chip Seong Bang, which was made by Hyo-Tong Yu, Jung-Rye Noh and Yun-Duk Park by the order of King Sechong in 1431 and published in eighty-five volumes in 1433. This work includes on hundred three families and two hundred eighty-one species plants, and makes a comprehensive survey of past studies on some medical books. To publish this work, some specialists such as Jung-Rye Noh were sent to China and they made an exchange of opinions with some specialists of China to correct some facts. Cullen soryliforia and Trigonella foenumgraecum of Laguminosae were described as a subtropical plant or tropical plant which had not been produced in our country Also, it includes several anti-cancer plants such as Panax schinseng and Rubia akane that are very helpful to the treatment of diseases of adult people.