The osteosarcoma is the most co1t1.mon primary malignant lesion of bone, even so it is relatively rare tumor in the jaw bones. It is derived from undifferentiated mesenchymal elements of bone, which from neoplastic osteoid and osseous tissue. It may affected primarily young adult males and more frequently mandible than maxilla. Mass, swelling and pain are the most presenting symptoms. Radiographic appearance will be sclerotic, in which bone formation is excessive: osteolytic, in which bone destruction predominates: and mixed, in which sclerotic and osteolytic changes are intermingled. We report a case of osteosarcoma on the mandibular ramus area in a 20 years old male with a brief review of the concerned literatures.