To determine the compatibilities of soft liming materials with denture cleansers by measuring the flexibility and elasticity and investigating the surface changes, 4 self-curing acrylic resin soft lining materials and 1 heat-curing silicone soft lining material were evaluated. 3mm thick x 20mm diameter discs of soft lining materials were individually bonded to a hard acrylic resin base as per manufacturers’instructions. Using an Instron universal testing machine, a static stress of $2kg/cm^2$ was applied for 30secs., the strain in compression was measured, giving an indication of the material’s flexibility. Elastic recovery was measured at 10secs. After removal of stress. Surface changes were investigated with Stereomicroscope. Then the specimens were immersed in 4alkaline peroxide denture cleansers and water as control group, tests were carried out at 1 day, 2 days, 7 days, 14 days and 30 days. The results were as follows : 1. Alkaline peroxide denture cleansers caused considerable porosity on the surface of selfcuring acrylic resin soft lining materials, and the most affected by the cleansers were Viscogel, Coe-Soft, Coe-Comfort, Lynal, in that order. 2. There was significant difference in flexibility between each soft lining material except for Coe-Comfort and Visco-gel, and every soft lining material was significant difference in elasticity. Especially Molloplast-B and Lynal were less flexible and more elastic than other soft lining materials(p<0.05). 3. The denture cleansers increased the flexibility and elasticity of the soft lining materials compared with control group(p<0.05), and Denalan, Polident, Kleenite, Efferdent affected the soft lining materials in that order. 4. There was significant difference in flexibility between each denture cleanser except for Denalan and Polident(p<0.05). Though Denalan and Polident, Denalan and Kleenite did not show significant difference in elasticity, other denture cleansers showed significant difference among each other(p<0.05). 5. Clinically Coe-Comfort, Coe-Soft and Visco-gel were incompatible with alkaline peroxide denture cleansers, and Lynal would be used within only 2 weeks. But Molloplast-B was compatible with alkaline peroxide denture cleansers.