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저빈도-고강도 경피신경전기자극이 혈장 $eta-endorphin$ 과 ACTH, 혈청 Cortisol 및 요중 17-OHCS 농도에 미치는 영향
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  • 저빈도-고강도 경피신경전기자극이 혈장 $eta-endorphin$ 과 ACTH, 혈청 Cortisol 및 요중 17-OHCS 농도에 미치는 영향
  • Effect of Acupuncture-like Transcutaneous Electrical Nerve Stimulation on Plasma $eta-endorphin$ and ACTH, Serum Cortisol and Urinary 17-OHCS Levels
저자명
박춘서,이재형,Park. Chun-Seo,Lee. Jae-Hyoung
간행물명
대한물리치료학회지
권/호정보
1994년|6권 1호|pp.5-15 (11 pages)
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대한물리치료학회
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이 논문은 한국과학기술정보연구원과 논문 연계를 통해 무료로 제공되는 원문입니다.
서지반출

기타언어초록

The purpose of this study was to examine the effect of electroanalgeia and $eta-endorphin$ action by acupuncture-like (Lof/Hil) transcutaneous electrical nerve stimulation (TENS) applied to acupuncture points. Twelve healthy adult male aged between 19 ann 25 were randomly assigned to TENS group (n=6) and naloxone group (n=6). Subjects of both groups were strongly stimulated TENS with 4 pps and $200{mu}s$ for 30 minutes on the LI 3 and LI 10 meridian points of dominant am. Naloxone group was injected naloxone hydrochloride before TENS application. The experimental pain threshold was measured by chronaxie meter CX-2 on the distal end of radius just before and after TENS application. The levels of plasma $eta-endorphin$ and ACTH. serum cortisol and urinary 17-OHCS were analyzed by radioimmunoassay (RIA) kits before and after TENS application. In TENS group, there was a significant increase of experimental pain threshold (p<0.01), plasma $eta-endorphin$ level (p<0.05), serum cortisol level (p<0,001) and urinary 17-OHCS levels (p<0.05) after TENS application. The plasma ACTH level was not significantly increased, but it showed an increasing tendency. In naloxone group, although there was a decreasing trend, ACTH and cortisol level did not show a significant change, but $eta-endorphin$ and 17-OHCS level were significantly decreased (p<0.01). The result of this study stewed that acupuncture-like TENS induced analgesic effect, such that the levels of plasma $eta-endorphin$, plasma ACTH, serum cortisol and urinary 17-OHCS were concomitantly increased with experimental pain threshold. It is suggested that the analgesic mechanism of the acupuncture-like TENS probably related to endogenous opioid component such as $eta-endorphin$.