For BEM analyses of the impact problems of dissimilar materials, the connected multi-region method using perfect bonded conditions on the interface boundaries was added to two-dimensional Laplace transformed-domain BEM program for a single region analysis. It was confirmed that the BEM results of impact problems of a single-region and multi-regions for a homogeneous isotropic material are agreed well. The two-dimensional Laplace transformed-domain BEM program combined with connected multi-region method was applied to analyse several impact problems of dissimilar materials. Also the feasibility of BEM impact analyses was investigated for dissimilar materials by the analysis of the BEM results for impact problems of dissimilar materials in terms of physical aspects. As for an application, the two-dimensional Laplace transformed BEM concerning impact problems of cracks at the interface of dissimilar materials and the determinating process of the dynamic stress intensity factors by extrapolation method are presented in this paper.