The effects of dietary buckwheat vegetables on the in vitro HMG-CoA reductase activity and lipids profiles of serum and liver in rats were evaluated . Buckwheat vegetables were cultivated in the range of 1-15cm of the plant height and dried. The content of rutin in the dried vegetables did not varied largely with the differences in the height of the vegetables. The water extract from buckwheat vegetables activited in vitro HMG-CoA reductase, activity up to 150% of control. Male rats were fed on purified diets. supplemented with0.12% cholesterol, containing dried buckwheat vegetables(BWV, 5% of diet) or rutin 90.25% of diet) . Dietary BWV and rutin, compared with basal diet tended to decrease the concentration of serum cholesterol. The ratio of HDL-cholesterol to total cholesterol were higher slightly in the rutin -fed group than in the other groups. The concentration of serum triacylglycerol was lower markedly in the rutin -fed groups than in the control groups, and BWV group being intermediate . The concentration of liver cholesterol was lower significantly in the BWV group than in the other groups. The results show an effective cholesterol-lowering action of buckwheat vegetables in serum and liver of rats fed on cholesterolemic diets. and that the hypocholesterolemic effects of buchwheat vegetables re not likely to be due to the modulation of the cholesterol synthesis rate.