The physiological significances of the upper and lower body on thermoregulation and sensation were studied in this paper. Experiments were carried out on 4 females in a climatic chamber conditioned at 1) $25^{circ}C ightarrow35^{circ}C ightarrow25^{circ}C$, 2) $25^{circ}C ightarrow15^{circ}C ightarrow25^{circ}C$, both with 50% R.H., covering the upper body (U) or lower body (L) with garments. 1. When the upper or lower body is covered or exposured respectively, the mean skin tempterature of upper body is higher than that of lower body. And upper body is more easily influenced by the environmental temperature than lower body. It means the skin temperatures of the upper body change faster than those of the lower body following the environmental changes. 2. In U and L, the skin temperatures of the upper limbs (thighs, upper arms) are lower than those of the peripherals (hands, feet). 3. Warm sensations and skin temperatures of the upper body showed high correlation and it was the case with cold sensations and skin temperatures of the lower body. 4. In high temperature condition $(25^{circ}C ightarrow35^{circ}C ightarrow25^{circ}C)$, mean skill temperature and rectal temperature in L were lower than in U. This lower rectal temperature in L is probably due to the insulation of the lower body with garments that promotes the heat radiation only in the high temperature environment.