The purposes of this study are (a)to investigate the effect of follow-up on the increase of response rate;(b)to analyze the effect of follow-up on the statistics by predetermined response rates ; therefore, (c)to describe the importance of high response rate and to suggest methods in order to increase response rate in mail survey. Telephone directory of Seoul was utilized as a sampling frame, and modified Total Design Method(TDM) was applied to collect the data. The results are summarized as follows. 1. Final response rate was 76.5% by 2 follow-ups. 2. The first follow-up with telephone call had a significant effect on increase of response rate. As a result, follow-up by postcard in TDM could be omitted in this method. 3. The second follow-up by registered mail did not have a significant effect. Therefore, use of this procedure is depending upon such research situtations as importance of high response rate and cost available. 4. Follow-ups helped to make collected sample highly representative. 5. Most questionnaires were arrived on the first half of data collection period in each follow-up. 6. Most of questionnaires were collected for 10 weeks. Accumulated responses could be fitted by exponential and logistic curve, simultaneously. The fitted curve suggested that eventually limited number of questionnaires by arrived. So, if researchers want higher response rate, they have to conduct more follow-ups. 7. Statistics in the predetermined response rate were not changed significantly. But replications are needed to generalize this result.