Anaplasmosis is a tick-borne disease mainly of cattle, sheep, and goats. Anaplasmosis in goat had been reported at last year by authors. The disease brought the economic losses in the goat farm in Chonbuk province. In order to treat the disease, a long-acting formulation terramycin injectable solution was used experimental animals which indigenous goats were sick with moderate anemia. We were devided into two groups was treated with single dosage (20mg /kg of body weight). one group was treated with single injection, the other group was treated with twice of the same dosage intramusculary injection. The results indicate that the use of long-acting terramycin would minimize clinical signs of anaplasmosis infection in goat. After treament the differrences of hematological appearences and parasitaemia were observed in the effect of terramycin treatment. obviously, increased value of RBC. HB and HCT, and parasitaemia by means of Giemsa staining and acrydine orange staining was observed decreased due to treatment.