These times many kinds of man-machine Interfaces using speech signal, speech recognizers or speech synthesizers, are proposed and utilized in practice. Especially speech synthesis system is widely used in our life. But its assessment method is still in its first stage. In this paper we propose a method to generate multi-syllable nonsense wordset for the purpose of synthetic speech assessment and applies the wordset to one commercial text-to-speech system. Some results about the experiment is suggested and it is verified that the method to generate a nonsense wordset can be used to assess the intelligibility of the synthesizer in phoneme level or in phonemic environmental level.