Purpose : To evaluate the radiologic findings of granulomatous colitis on double contrast barium enema andchanges on follow-up studies. Materials and Methods : Serial double contrast barium enemas of six patients withgranulomatous colitis confirmed by endoscopic biopsy were reviewed. We analyzed the radiologic findings and theirfollow-up changes, including aphthous ulcers, lymphoid hyperplasia, deep ulcers, cobble stone appearance,geographic ulcers, asymmetric involvement of ulcers, skip lesions, sinus tract, fistula formation,pseudosacculation, focal stricture, and small bowel involvement. Results : Pretreatment double contrast baruimenema findings were aphthous ulcers in five patients, deep ulcer in six, cobble stone appearance in five,longitudinal geographic ulcers in two, fistulas in one, pseudosacculations in two, focal stricture in one, andpseudopolyps in six. Also, anal ulcers are observed in two patients, asymmetric involvement of ulcers in three,skip lesions in four, and small bowel involvement in five in five patients proved to have inactive disease aftertreatment, aphthous ulcers and deep ulcers disappeared. Geographic ulcers of two patients and anal ulcer of onepatient decreased in size or depth. Pseudosacculation in one patient disappeared. Pseudopolyps decreased in twopatients, increased in one, and decreased after increase in two. One patient whose disease remained active aftertreatment showed maintenance or increase of ulcers or fistula. And their pseudosacculation or focal strictureunchanged and pseudopolyps decreased. Conclusion : The major radiologic findings of chronic granulomatous colitison double contrst barium enema are aphthous ulcer, deep ulcer, cobble stone appearance, discontinuity of thelesion, and coexistence of ulcers and pseudopolyps. And, double contrast barium enema is good follow-up modalitybecause its findings correlate with clinical course of the granulomatous colitis after treatment.