A general formulation of the design optimization problem with the random parameters is presented here. The formulation is based on the stochastic finite element second-order perturbation method ; it takes into full account of the stress and displacement constraints together with the rates of change of the random variables. A method of direct differentiation for calculating the sensitivity coefficients in regard to the governing equation and the second-order perturbed equation is derived. A gradient-based nonlinear programming technique is used to solve the problem. The numerical results are specifically noted, where the stiffness parameter and external load are treated as random variables.