This studies concern the separation of aqueous boric acid solution and same solution containing silica using cellulose acetate RO S/W 4040 module manufactured by Hydranautics Co. The operating conditions of the applied pressures, temperatures, and feed flow rate are also investigated to characterize the permeabilities, biroc acid recovery, and silica rejection, so that the optimum operating conditions would be found out. In the case where the operating conditions are the temperature 35$^{circ}$C, The pressure 20atm, and the feed flow rate 2.82 l/min, for the boric acid aqueous solution, the boric acid recovery 58.7% and the permeation rate 2.82 l/min were obtained. And also the results showed the boric acid recovery 68.1% and the permeation rate 1.56 l/min at the operating conditions, 35$^{circ}$C and 10atm. For the boric acid solution containing silica, when the feed solution are at the conditions of 35$^{circ}$C and 3.2atm, the boric acid recovery 69.7%, the silica rejection 97.5% and the permeation rate 0.47 l/min were obtained. And the operating conditions were at 35$^{circ}$C, 20atm and the feed flow rate 2.92 l/min, the results showed the boric acid recovery 56.4%, the silica rejection 96.1% and the permeation rate 2.72 l/min.