- HRccine(HFRS-virus vaccine)의 급성독성
- ㆍ 저자명
- 임동문,백영옥,김달현,박관하,조정식,이영순
- ㆍ 간행물명
- 한국독성학회지
- ㆍ 권/호정보
- 1995년|11권 1호|pp.133-136 (4 pages)
- ㆍ 발행정보
- 한국독성학회
- ㆍ 파일정보
- 정기간행물| PDF텍스트
- ㆍ 주제분야
- 기타
이 논문은 한국과학기술정보연구원과 논문 연계를 통해 무료로 제공되는 원문입니다.
HRccine(HFRS-virus vaccine) was administered subcutaneously or intragastrically to Spargue Dawley rats and subcutaneously to Japanese white rabbits to investigate the acute toxicity. $LD_50$ values were above 600 times the expected clinical dose in both animals. There were no differences in body weight changes, clinical signs and autopsy findings between all treated groups and control group in both animals. Therefore, it was concluded that HRccine is a very safe substance.