The objective of this study is to predict the reliability of the electronic control module at ROD control system in nuclear power plant. Maintaining of the reliability is important issue in the complext system like nuclear plower plant, military equipment, satelite system, etc., because the failure of reliability brings etravagant economic loss and deteriorates public acceptance. In addition to the prediction of reliability, the fators affect the reliability including operating condition, environment, temperature and quality factors were analyzed and simulated. The result shows that the quality factors are more critical for the higher reliability than other two factors.