NMR measurement has been studied for protons in pre-polarized flowing water by a separated detector working at high field far away from the measured field region where the transition of protons is occurred by the pertur-bation of RF energy. The conditions for NMR signal were optimized on the amplitude and frequency of modulation field, the RF field of detector, water speed, and RF field at the measured field region. The NMR signal with the full width of 320 nT at the half maximum in Lorentzian curve and with signal to noise ratio of 10.5 was measured in the range from a few ${mu}T$ to mT, and its shape and amplitude were independent of the measured field intensity and its uniformity.