In order to treat effectively various type of wastewater discharged from the manufacture factory of organic phosphorous agricultural pesticides by the activated sludge process. The acclimation test of sludge was carried out by the dilution of completely mixed raw wastewater. The results of experiment were obstained as follows. 1. The moderate dilution rate of mixed raw wastewater was founded to about 30 times. 2. The available range of BOD-SS loading was 0.1~0.15 $kgcdot BOD/kgcdot SScdot day$ and it was similar to the case of extended aeration activated sludge process. 3. After the acclimation of activated sludge, the concentration of MLSS was 2000 mg/L, removal efficiency of BOD more than 90%, and SVI 100, respectively. 4. The oxygen respiratory rate of acclimated sludge was $47 mgcdot O_2/gcdot hr$ and this was increased about 5 times than $10 mgcdot O_2/gcdot hr$ of ordinary sludge.