This study was performed to investigate the negative side effects of video display terminal (VDT) work on the human body and to provide data for preventing VDT syndrome. A questionnaire survey was made to 339 VDT workers at 22 offices in Taegu, Kyungpook and Kyungnam areas from July 1 to August 31, 1994, and 280 of them were finally used for statistical analysis. The VDT syndrome in the present study inclhded five factors, namely as eye-related symptom, psychological symptom, general body symptom, musculoskeletal symptom, and skin-related symptom, and the estimates of Crombach coefficients of the five factors were 0.954, 0.952, 0.953, 0.957, and 0.955, respectively, showing very high reliability. In view of socio-economical characteristics, the symptoms of female were higher than those of male in the order of musculoskeletal symptom, eye-related symptom, skin-related symptom and psychological symptom. The age group of 30 years or less was higher than the older groups in the order of musculoskeletal symptom, eye-related symptom, psychological symptom and skinrelated symptom. The group of lower education level showed higher skin-related symptom. The psychological symptom and skin-related symptom increased as the amount of smoking increased. Higher eye-related symptom was observed in the group without glasses. In the job-related variables, the group of working on programming and data input showed higher eye-related symptom and psychological symptom. The group of working on programming and graphic design showed higher musculoskeletal symptom and skin-related symptom. The skin-related symptom increased as the total time of VDT operation per day increased. The group of working 2-4 hours followed by 15 minutes rest was higher in musculoskeletal symptom and psychological symptom. Higher musculoskeletal symptom was observed from the group working on Friday and Sunday. The group of 1 year or less working showed higher in skin-related symptom. In relation with the VDT type, all symptoms except skin-related symptom were higher in the group using monochrome monitor. As showed above, the questionnaire could be a tool for evaluating VDT syndrome and prevention of the syndrome would be possible by a comprehensive consideration of factors including socio-economic characteristics, job-related variables and VDT type.