An integrated fault diagnosis system for heterogeneous manufacturing environments is developed. This system has a contrast with existing diagnosis systems in the respect that they are mostly for diagnosing faults on individual machines. In addition to the usual (e.g., audio, electrical) diagnostic signals, the characteristics of products from the machines are considered as the unifying diagnostic parameters among heterogeneous machines in the diagnosis. The system is composed of a knowledge representation scheme and a diagnostic query processing mechanism. Its knowledge representation scheme allows the diagnostic knowledges from heterogeneous unit diagnostic systems to be uniformly expressed in terms of the causal relations among relevant data items. It is flexible in the sense that causes for one relation can be effects for another may be reflected on our knowledge representation scheme. The diagnosis mechanism is based on a probabilistic inferencing method. This probablistic diagnosis mechanism provides more general diagnosis than existing ones in that it accommodates multiple causes and takes complication among causes into account. These scheme and mechanism are applied to a typical example to demonstrate how our system works.