The active control system of structural vibration using a hydraulic actuator is developed. The developed system consists of three parts : a hydraulic unit, an actuator unit and a control unit. Structural vibration is sensored by the accelerometer attached to the structure and reduced by the optimally controlled motion of active mass giving anti-phase inertia force to the structure. It is experimentally confirmed that the vibration level of model structure is reduced to about 1/6 by the developed active control system.