Clincal observation was made on 76 cases of thyroglossal duct cyst and fistula with brief review of literature. All of the cases were diagnosed and treated surgically in Kyung Hee University Hospital from 1971 to 1993. The following results were obtained. 1) Most cases were under 20 years old(72.3%). and 49(64.5%) cases were male and 27(35.5%) cases were female. 2) Morphologically cystic type were found in 60(78.9%) cases and fistula type were 16(21.1%) cases. 3) Fluctuating cystic mass and pus discharge from fistula on just below the hyoid bone at midline of anterior neck were most common symptoms and signs. 4) 9(11.8%) cases were recurrent type and 4(5.3%) cases were recurred twice, at the time of first visit. 5) There were 2(2.6%) cases of having connection with the thyroid gland which were identified grossly on the operation field. 6) The entire cases were operated according to the Sistrunk procedure under the general anesthesia. 7) There was no recurrence and other complication except 4(5.3%) cases of wound infection.