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생약복합제제(삼황사심탕(三黃瀉心湯), 황련해독탕(黃連解毒湯))가 흰쥐의 실험적 고지혈증에 미치는 영향
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  • 생약복합제제(삼황사심탕(三黃瀉心湯), 황련해독탕(黃連解毒湯))가 흰쥐의 실험적 고지혈증에 미치는 영향
  • Effect of Composite Preparation of Crude Drugs on Experimentally Induced Hyperlipemia in Rats -Sam Whang Sasim Tang and Whang Ryun Haedok Tang
저자명
한성준,정명현,Han. Sung-Jun,Chung. Myung-Hyun
간행물명
생약학회지
권/호정보
1996년|27권 4호|pp.397-407 (11 pages)
발행정보
한국생약학회
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정기간행물|
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이 논문은 한국과학기술정보연구원과 논문 연계를 통해 무료로 제공되는 원문입니다.
서지반출

기타언어초록

This study was attempted to investigate the effect of Composite Preparation (Sam Whang Sasim-Tang: SWST, Whang Ryun Haedok-Tang: WRHT) on the activities of GOT and GPT, the content of total lipids, triglyceride, total cholesterol. Phospholipid and ${eta}-lipoprotein$ in the serum, and the change ratio of body and liver weight in the experimentally induced hyperlipemic rats, making use of the extract 150, 200, 300 and 500 mg/kg p.o. Significant test was performed by comparision with the values of corresponding experimentally hyperlipemic rats. The activities of S-GPT was significantly decreased in all dose of SWST and WRHT respectively. The activities of S-GPT was significantly decreased in dose of SWST 500 mg/kg and in all dose of WRHT respectively. The content of total lipids, triglyceride, total cholesterol and phospholipids were significantly decreased in all dose of two the extract. The rate of decrease on total lipids and triglyceride were remarkable in dose of SWST 300, 500 mg/kg and WRHT 200, 500 mg/kg, and then the content of total cholesterol was more remarkable in dose SWST 300, 500 mg/kg, and WRHT 150, 300 mg/kg, and the content of phospholipids was more remarkable in dose of the extract 150, 200 and 300 mg/kg. The content of ${eta}-lipoprotein$ was significantly decreased in dose of WRHT 150, 200 and in all dose of SWST. Increase ratio of the body and liver weight were significantly decreased in dose of two the extract 300, 500 mg/kg respectively.