Purpose : To evaluate the air contamination of the gelfoam in the angio-intervention room. Materials andMethods : After exposing four groups of gelfoam(group A1 : gelfoam fragment, group A2 : gelfoam fragment+ saline +contrast media, group B1 : gelfoam powder, group B2 : gelfoam powder + saline + contrast media) to air in theangio-intervention room, we inoculated gelfoam in each group to 30 agar plates each at every fifteen minutes forone hour with aseptic cotton buds. Cultivating them in the incubator for one day, we evaluated the growth ofbacteria or fungus. Results : Out of 480 inoculated agar plates, the growth of coagulase(-) staphylococci wasvisible in 14 ; in group A1, two at 30 minutes, three at 45 minutes, and four at 60 minutes ; in group A2, one at45 minutes and two at 60 minutes ; in group B1 and B2, one each at 45 minutes. The stastical analysis on bacterialcontamination according to time sequence and group revealed no significance(p〉0.05). Conclusions : If gelfoam isexposed to room air for less than 30 minutes, it is possible to reduce contamination by air-borne bacteria. Sincecoagulase-negative Staphylococci resistant to commonly used antibiotics, it is ideal to reduce exposure of gelfoamto room air for less than 30 minutes.