The aerodynamic design of the two-stages of centrifugal compressors in an 1.2MW industrial gas turbine is completed with the application of numerical analyses. The final shape of an intake, the axial guide vanes and a return channel is determined using several interactions between design and two-dimensional turbulent flow analysis, focused on the minimum loss of internal flows. The one-dimensional turbulent flow analysis, focused on the minimum loss of internal flows. The one-dimensional design and prediction of aerodynamic performances for the compressors are performed by two different methods; one is a method with conventional loss models, and the other a method with the two-zone model. The combination methods of the Betzier curves generate three-dimensional geometric shapes of impeller blades which are to be checked with a careful change of aerodynamic blade loadings. The impeller design is finally completed by the applications of three-dimensional compressible turbulent flow solvers, and the effect of minor change of design of the second-stage channel diffuser is also studied. All the aerodynamic design results are soon to the verified by component performance tests of prototype centrifugal compressors.