This paper presents the ECG data compression using wavelet transform (WT) and adaptive fractal interpolation (AFI). The WT has the subband coding scheme. The fractal compression method represents any range of ECG signal by fractal interpolation parameters. Specially, the AFI used the adaptive range sizes and got good performance for ECG data cmpression. In this algorithm, the AFI is applied into the low frequency part of WT. The MIT/BIH arhythmia data was used for evaluation. The compression rate using WT and AFI algorithm is better than the compression rate using AFI. The WT and AFI algorithm yields compression ratio as high as 21.0 wihtout any entropy coding.