To enhance cellulose hydrolysis f Humicola insolens cellulase (HIC) was empolyed with immobilized glucose isomerase(IGI). Optimun pH and temperature for HIC were 6.5 and 55$^{circ}C$, respectively, whereas those for IGI were 7.0 and 60$^{circ}C$, respectively. Optimun loading size of IGI was 200mg(130 untis) with 15units of HIC. Reaction conditions were determined to be as follows: 55$^{circ}C$,pH 6.5, HIC 15 units and IGI 130 units. After 24h hydrolysis, more than 65% of avicel was converted to glucose and fructose; in contrast, the conversion ratio of control was 40%.