In general, printing inks are mainly composed of pigments and vehicles. Its characteristics are affected, to a greater or lesser extent, by the size and distribution of the pigment particles in the dispersion. Color strength, transparency and gloss generally increases with an decrease in particle size of pigments. On the contrary, opacity, lightfastness tend to increases with an increase in particle size of pigments In this work, we have investigated an effect of surface area of pigments on the physical properties of printing of printing ink which made up vehicles for sheet fed and organic pigment Lake Red C(C.I.Pigment Red 53:1) that different surface area and particle size. It was found that gloss, tack and yield value increases with an increase in surface are of pigments, but grindness is reduced.