녹차 음용이 알루미늄을 투여한 흰쥐의 혈청 효소 활성도에 미치는 영향을 알아보고자 흰쥐 Sprague-Dawley계 수컷 25마리를 .5개 그룹 즉 대조군, 녹차음용군, 녹차와 알루미늄 용액 혼합군, 먼저 녹차를 2주 동안 투여 한 후에 알루미늄 용액만 2주 동안 투여한 군, 알루미늄 용액만 투여한 군으로 나누어 4주 동안 사육하여 aspartate amino transferase(AST), alanine amino transferase (ALT), lactate dehydrogenase (LDH) cholinesterase(ChE)를 조사하였다. 체중변화는 대조군에 비하여 전 실험군이 감소하였는데 특히 알루미늄과 녹차를 같이 투여한 군의 체중이 감소되었다. ALT는 대조군에 비하여 별다른 차이점을 보이지 않았으나 녹차와 같이 투여한 군에 비하여 알루미늄 용액만 투여한 군이 높았고 AST는 대조군에 비하여 녹차 투여군만 감소하였고 녹차와 알루미늄을 같이 투여한 군은 증가하였으나 알루미늄 용액만 투여한 군에 비하여 낮았다. LDH는 대조군에 비하여 전 실험군이 증가하였으며 특히 알루미늄 용액만 투여한 군은 녹차를 투여한 군에 비하여 유의적으로 증가하였고 ChE는 대조군에 비하여 알루미늄 용액만 투여한 군은 유의적으로 감소하였으나 알루미늄 용액만 투여한 군에 비하여 녹차를 같이 투여한 군은 증가하였다.
This study was performed to investigate the effects of green tea activites in rats with administration of aluminum in drinking green tea. Male Sprague-Daweley rats were divided into five groups consisting of the control, aqueous green tea at the level of 1.5%, a aquous green tea(1.5%) and aluminum sulfate solution 500ppm, before the 2 weeks administration by aquous green tea(1.5%) and after the 2 weeks aluminum sulfate solution 500ppm, aluminum sulfate solution 500ppm. After 4weeks of feeding, serum enzymes activites were measured for experimental rats, and analyzed the activites of alanine amino trans aminase(ALT), asparate amino transminase(AST) , lactate dehydrogenase(LDH), cholinesterase(ChE). Comparing to control group, Alanine amino trans aminase (ALT) was decreased in aqueous green tea administrated group and increased significantly administration by aluminum sulfate solution 500ppm group. Alanine amino trans aminase(ALT) was decreased administration by aqueous green tea group and Increased addition to aluminum sulfate solution 500ppm group as compared to control group. Lactate dehydrogenase(LDH) was increased compared to control group by experimental group and increased significantly administration by aluminum sulfate solution 500ppm. Cholinesterase (ChE) activity was decreased compared to control group by experimental group.
