Purpose : To evaluate prognosis-related CT findings in hypoxic ischemic encephalopathy. Materials and Methods: For the purpose of prognosis, 28 children with a clinical history and CT findings suggestive of hypoxic ischemicencephalopathy (HIE) were restrospectively reviewed. The diagnostic criteria for HIE, as seen on CT scanning, wereas follows : 1, ventricular collapse ; 2, effacement of cortical sulci ; 3, prominent enhancement of corticalvessels ; 4, poor differentiation of gray and white matter ; 5, reversal sign ; 6, obliteration ofperimesencephalic cistern ; 7, high density on tentorial edge, as seen on precontrast scans ; and 8, low densityin thalamus, brain stem and basal ganglia. On the basis of clinical outcome, we divided the patients into threegroups, as follows : group I(good prognosis) ; group II(neurologic sequelae), and group III(vegetative state orexpire), and among these, compared CT findings. Results : There were thirteen patients in group I, six in groupII, and nine in group III. Ventricular collapse, effacement of cortical sulci, and prominent enhancement ofcortical vessels were noted in all groups, whereas poor differentiation of gray and white matter, reversal sign,obliteration of perimesencephalic cistern, high density on tentorial edge, on precontrast scan, and low density inbrain stem and basal ganglia were observed only in groups II and III. Conclusion : CT findings showed distinctdifferences between groups in whom prognosis was good, and in whom it was poor. An awareness of poor prognostic CTfindings may be clinically helpful in the evaluation of patients with hypoxic ischemic encephalopathy.