In order to investigate the characteristics of sound-structure interaction plate having a cut-out, we modeled a rectangular cavity and the flexible plate of the cavity. Because the particle velocity of air is the same as that of plate on the plate, we could easily redefine vibration equation using the velocity potential. We calculated the natural frequencies of plate using orthogonal polynomial functions which satisfy the boundary conditions in the Rayleigh-Ritz method. For the change of vibration characteristics, the effect of sound-structure interaction is more dominant than that of cut-out size.