This paper describes motion errors due to acceleration and deceleration types of servo motors in NC machine tools. Motion errors are composed of two components : one is due to transient response of a servomechanism and the other comes from gain mismatching of positioning servo motors. It deals with circular interpolation to identify motion errors by using Interface card. Also in order to minimize motion errors, this study presents an effective method to optimize parameters which are connected with motion errors. The proposed method is based upon a second order polynomial regression model and it includes an orthogonal array method to make the effective results of experiments. The validity and reliability of the study were verified on a vertical machining center equipped with FANUC 0MC through a series of experiments and analysis.