Sealing an oil-air mixture plays important roles to have an enhanced lubrication for high speed spindle. High speed spindles require non-contact type sealing mechanism. In this study, an optimum seal design to minimize leakage is concerned in the aspect of flow control. This paper categorizes geometries of mostly used non-contact type seals and analyzes each leakage characteristics to minimize a leakage on sealing area. Effect of minimum clearance and its position are considered according to variation of detail geometry. The estimation of non-leaking property is determined by amount of pressure drop in the leakage path assuming constant leakage flow. To simulate an oil jet or oil mist type high speed spindle lubrication, the working fluid is regarded as two phases that are mixed flow of oil phase and air phase. Both of the turbulence and the compressible flow model were introduced in CFD(Computational Fluid Dynamics) analysis. Design parameters has been induced to minimize leakage in limited space, and a methodological study on geometrical optimization has been conducted.