The heat rejection to coolant is a dominant factor for building vehicle cooling system such as radiator and cooling fan. Since the vehicle cooling system also has effects on fuel consumption and noise, the study of heat rejection to coolant has been emphasized. However, the study on heat rejection to coolant has been mainly focused on the field that related to the characteristics of combustion and localized heat loss. It is no much of use in design for the entire cooling system because it is focused on such a specific point. In this work, the heat rejection rate to coolant for four different engines are obtained to derive a simple heat transfer empirical formula that can be applied to the engine cooling system design, and it is compared with the other studies. Also, to observe effects of engine operation factors and heat transfer factors on coolant, we measured the metal temperature and the heat rejection rate. The heat rejection to coolant does not depend significantly upon the coolant flowrate, but mainly upon the amount of air fuel mixture and the air fuel ratio as long as the composition of coolant does not change. The reduction of heat rejection to coolant did not effectively improve the fuel consumption, but was mostly converted to raise the exhaust gas temperature and the oil temperature.