In the design of tall building system, the wind loading can be more dominant factor than earthquake loading, and thus, it is important to check the stability and human comfort against wind. Experimental wind tunnel test is usually performed to predict wind behavior of a tall building, however, the test is not cost-effective in the preliminary stage for various structural models of tall building systems. In this regard, the study is focused on the numerical wind analysis of the tall building with and without tuned mass dampers based on the three dimensional model of wind loads and building behavior. As a numerical result, an asymmetrical 102-story tall building is presented to show the results of root mean squares of build responses with and without tuned mass dampers.