The main objective of this study is to analysis the relationship between productivity measurement model which describe and explain R&D(Research & Development) productivity based on production function of Cobb-Douglas and the structure of the R&D investment. The model focuses on the variables related to R&D investment in order to measure the efficiency of R&D largely. So, the proposed model describe the relationship between output(or / input) and factors of production such as capital cost, labor cost and R&D expense, etc. These factors are associated with a signigicant positive correlation between productivity and R&D investment.